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JACQUES MORTIER

Professor (1st class, O-Chem),  IUF Honorary Member, PhD

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New: ARENE CHEMISTRY BOOK

Arene Chemistry: Reaction Mechanisms and Methods for Aromatic Compounds Copyright © 2016 by John Wiley & Sons, Inc., Jacques Mortier (Editor), ISBN-13: 978-1118752012, ISBN-10: 1118752015 1st Edition.

1118752015

In Arene Chemistry Jacques Mortier has brought together contributions from leading practitioners in universities and research institutes from around the world to create a concise but comprehensive text on aromatic chemistry. The book consists of 32 chapters, in 10 parts, which cover both classical aromatic chemistry, as well as very recent developments in the field. The 959 pages however do not feel weighty, and it is easy to find one’ s way around the topics… This comprehensive book ventures successfully to put all of aromatic chemistry into one convenient sized and handy volume. The editor and contributors are to be congratulated for taking on such an ambitious project. They have effectively condensed the essential material, and made an ideal source of information; whether one is looking to locate specific conditions for a single transformation, or whether one just wishes to read up on the underlying mechanistic and synthetic principles of a particular topic, this book will be an ideal starting point. The book will be of interest to all researchers in industry and academia working with arene compounds, as well as advanced undergraduates wishing to develop their knowledge of this essential field.
Full text: George Weaver, Applied Organometallic Chemistry, March 2018, e4129

The broad covering of topics, made possible by the collaboration of world-renowned experts in different fields of organic chemistry and by a good balance in depth of coverage, positions “Arene Chemistry: Reaction Mechanisms and Methods for Aromatic Compounds” as a deskbook that would be extremely useful for students of advanced courses of organic chemistry, instructors and professors, as well as experienced chemists in both academy and industry, and to those interested in arene chemistry and its application.
Full text: Oleg M. Demchuk, Chemistry International, July-September 2018, vol. 40, No 3, 42-44

MAIN AWARDS
— Honorary member of the “Institut universitaire de France” (University Institute of France – IUF, 1998)
— Medal of the city of Rennes (1999)
— Auditor at the Institut des Hautes Études de l’Entreprise (2002, Paris)

CURRENT RESEARCH
From novel organic and organometallic methodologies to fine chemical synthesis, biologically active molecules and molecular materials
— Directed Metalation (New concepts in alkyllithium activation, regio and chemoselective lithiations in benzene ring…)
— Mechanistic Studies (polar organometallics)
— Synthesis of Pro-Apoptotic Gossypol Analogs by Metalation Reactions

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RECENT PUBLICATIONS AND PATENTS
(VIEW COMPLETE LIST)

Main author(s) identified by *.

• D. M. T. Nguyen, L. M. T. Do, V. T. Nguyen, W. Chavarisi, J. Mortier, K. P. P. Nguyen* “Phenolic Compounds from the Lichen Lobaria orientalisJ. Nat. Prod. 2017, 80, 261

 Arene Chemistry: Reaction Mechanisms and Methods for Aromatic Compounds, J. Mortier Ed., John Wiley & Sons, Inc., Hoboken NJ, USA (Book)  (2016) Front Matter (pages i–xxvii)

 Asymmetric Nucleophilic Aromatic Substitution by A.-S. Castanet, A. Boussonnière and J. Mortier*, Chapter 8, in Arene Chemistry: Reaction Mechanisms and Methods for Aromatic Compounds, J. Mortier Ed., John Wiley & Sons, Inc., Hoboken NJ, USA (Book Chapter) (2016)

• Directed Metalation of Arenes with Organolithiums, Lithium Amides, and Superbases by F. R. Leroux* and J. Mortier*, Chapter 26, in Arene Chemistry: Reaction Mechanisms and Methods for Aromatic Compounds, J. Mortier Ed., John Wiley & Sons, Inc., Hoboken NJ, USA (Book Chapter) (2016)

 Preface by J. Mortier in Arene Chemistry: Reaction Mechanisms and Methods for Aromatic Compounds, J. Mortier Ed., John Wiley & Sons, Inc., Hoboken NJ, USA (2016)

• M. Belaud-Rotureau, A.-S. Castanet, T. H. Nguyen, J. Mortier* “Uncatalyzed CO2Li-Mediated SNAr Reaction of Unprotected Benzoic Acids via Silicon Trickery” Aust. J. Chem. 2016, 69, 307

• T. T. T. Nguyen, A. Boussonnière, E. Banaszak, A.-S. Castanet, K. P. P. Nguyen, J. Mortier* “Chemoselective Deprotonative Lithiation of Azobenzenes. Reactions and Mechanisms” J. Org. Chem. 201479, 2775  Supporting Information

• T. T. T. Nguyen, A. Boussonnière, E. Banaszak, A.-S. Castanet, K. P. P. Nguyen, J. Mortier* “Selective Lithiation of Azobenzenes” Synfacts 2014, 10, 850

• J. Mortier*, A.-S. Castanet, N. T. T. Chau Gossypol and apogossypol derivatives, preparation thereof and use thereof” US Patent US8455540B2 (2013)

 J. Mortier*, A.-S. Castanet, A. Nourry, M. Belaud-Rotureau “Process for Preparing Chemical Compounds of Interest by Nucleophilic Aromatic Substitution of Aromatic Carboxylic Acid Derivatives Supporting at Least One Electro-Attractive Group” US Patent US2012330056A1 (2012)

• R. Aissaoui, A. Nourry, A. Coquel, T. T. H. Dao, A. Derdour, J.-J. Helesbeux, O. Duval, A.-S. Castanet, J. Mortier* “Ortho-Lithium/Magnesium Carboxylate-Driven Aromatic Nucleophilic Substitution Reactions on Unprotected Naphthoic Acids” J. Org. Chem. 201277, 718  Supporting Information

 J. Mortier*, A.-S. Castanet, M. Belaud-Rotureau “Method for Preparing Chemical Compounds of Interest by Nucleophilic Aromatic Substitution of Aromatic Carboxylic Acid Derivatives Supporting at Least One Electro-Attractive Group” US Patent US2012316337A1 (2012)

• D. Tilly*, J. Magollan, J. Mortier* “Directed Remote Aromatic Metalations: Mechanisms and Driving Forces” Chem. Eur. J. 201218, 3804

• J. Mortier*, A.-S. Castanet, A. Nourry, M. Belaud-Rotureau “Procédé de substitution nucléophile aromatique à partir d’acides difluorobenzoïques” FR Patent FR2961204 (2011)

 N. H. Nguyen, C. Len, A.-S. Castanet,* J. Mortier* Selectivity in C-Alkylation of Dianions of Protected 6-Methyluridine” Beilstein J. Org. Chem. 20117, 1228   Supporting Information

 J. Mortier* “The Meyers Reaction (1994-2010)” Curr. Org. Chem. 201115, 2413

 J. Mortier*, A.-S. Castanet, A. Nourry, M. Belaud-Rotureau “Method for Preparing Chemical Compounds of Interest by Nucleophilic Aromatic Substitution of Aromatic Carboxylic Acid Derivatives Supporting at Least One Electroattractive Group”  WO Patent WO2011101604A1 (2011) (English version)

 J. Mortier*, A.-S. Castanet, M. Belaud-Rotureau Method for Preparing Chemical Compounds of Interest by Aromatic Nucleophilic Substitution” WO Patent WO2011101599A1 (2011) (English version)

 T. T. Le, N. T. T. Chau, T. T. Nguyen, J. Brien, T. T. Thai, A. Nourry, A.-S. Castanet, K. P. P. Nguyen, J. Mortier* Evidence for a Trianion Intermediate in the Metalation of 4-Hydroxy-6,7-dimethoxy-8-methyl-2-naphthoic Acid. Methodology and Application to Racemic 5,5’-Didesisopropyl-5,5’-dialkylapogossypol Derivatives” J. Org. Chem. 201176, 601  Supporting Information

 J. Mortier*, A.-S. Castanet, M. Belaud-Rotureau Procédé de préparation de composés chimiques d’intérêt par substitution nucléophile aromatique de dérivés d’acides carboxyliques aromatiques”  FR Patent FR2956662A1 (2011)

 J. Mortier*, A.-S. Castanet, N. T. T. Chau Gossypol and apogossypol derivatives of general formula (1), preparation thereof and use thereof” US Patent US20100331398A1 (2010), EP Patent EP2231573 (2010)

 J. Mortier*, A.-S. Castanet, E. Banaszak “ Procédé de préparation d’omega-alcynylsilanes” FR Patent FR2942228A1 (2010)

 M. Belaud-Rotureau, T. T. Le, T. H. T. Phan, T. H. Nguyen, R. Aissaoui, F. Gohier, A. Derdour, A. Nourry, A.-S. Castanet, K. P. P. Nguyen, J. Mortier* ”Synthesis of N-Aryl and N-Alkyl Anthranilic Acids via SNAr Reaction of Unprotected 2-Fluoro and 2-Methoxybenzoic Acids by Lithioamides”  Org. Lett201012, 2406    Supporting Information

 D. Tilly, J.-m. Fu, B.-p. Zhao, M. Alessi, A.-S. Castanet, V. Snieckus*, J. Mortier* “On the Mechanism of the Directed ortho and remote Metalation Reactions of N,N-Dialkylbiphenyl-2-carboxamides” Org. Lett. 201012, 68  Supporting Information

(VIEW COMPLETE LIST)

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